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A study found linked between healthy lifestyle habits and living longer. AdvertisementHealthy lifestyle choices could help us live up to five years longer, regardless of our genetic makeup, a study suggests. At the same time, a healthy lifestyle appeared to offset the effects of genes linked to a shorter lifespan by 62%. Making favorable lifestyle choices despite having genes linked to a shorter lifespan was linked to living 5.22 years longer than those who made unfavorable choices. However, she said that the effects of lifestyle factors in the study were notable because they suggest that while we can't change our genes, healthy habits may lessen their impact.
Persons: , Liz Williams, wasn't, Williams, It's Organizations: Service, University of Sheffield, Centers for Disease Control
For almost 10 years, I struggled with a type of OCD known as sexual orientation OCD (SO-OCD). When I moved to a progressive city, I accepted my queerness and now I'm engaged to the woman I love. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . AdvertisementAlegra Kastens, LMFT, founder of the Center for OCD, Anxiety, and Eating Disorders, told me: "OCD doesn't exist in a vacuum. She had a queer friend who lived in the building, and that friend flirted with me.
Persons: , I'd, You've, Alegra, queerness Organizations: Service, Michigan Locations: Denver
Scientists identify ‘degrees of Kevin Bacon’ gene
  + stars: | 2024-05-02 | by ( Katie Hunt | ) edition.cnn.com   time to read: +6 min
Even humble fruit flies organize themselves into regularly spaced clusters, researchers have found. Within those social networks, certain individuals will often stand out as “gatekeepers,” playing an important role for cohesion and communication within that group. New research published Tuesday in the journal Nature Communications has identified a gene responsible for regulating the structure of social networks in fruit flies. The study opened up new opportunities for exploring the molecular evolution of social networks and collective behavior in other animals. FLPA/ShutterstockThe gene behind fruit fly social networksThe researchers investigated a number of gene candidates in fruit flies, a common lab organism used in the study of genetics.
Persons: , Kevin Bacon, Bacon, Joel Levine, Rebecca Rooke, ” Levine, Levine, , ” Allen J, Moore, wasn’t, ” Moore Organizations: CNN, Nature Communications, University of Toronto, University of Georgia’s Locations: Philadelphia, University of Toronto Mississauga
But this week, investigators finally revealed her identity: Patricia Kathleen McGlone, a 16-year-old who lived in Brooklyn. NYPDInvestigators believe Patricia was killed in late 1969 or early 1970 and buried in the basement of the building. With advanced forensics, they determined her parents’ identity and where they lived in Brooklyn, and scoured through local public documents. Decades earlier, around the time Patricia was believed to have been killed, the building housed a nightclub called The Scene, Glas said. The New York City Medical Examiner’s Office determined in 2003 that the skeleton belonged to a teenage girl who stood 5-foot-2.
Persons: CNN —, , Ryan Glas, Jane Doe ”, Patricia Kathleen McGlone, haven't, Patricia, Glas, Steve Paul, Jimi Hendrix, ” Glas, , Bernard McGlone, Patricia Gilligan, Patricia’s Organizations: CNN, New York City Police Department, Brooklyn . Police, NYPD, Police, The New York, Medical, Office, Catholic Locations: Manhattan, New York City, Brooklyn, Glas
Plenty of retailers have kicked off Mother's Day sales to make it easier to get a thoughtful present without breaking the bank. No matter what type of mom you have, we've gathered the best Mother's Day deals on flower delivery, jewelry, smart photo frames, and more. It's still early, so we expect plenty more Mother's Day sales to kick off as the holiday approaches. 5 best Mother's Day sales 1-800-Flowers: Get up to 40% off Mother's Day arrangements. More Mother's Day salesFrequently asked questionsWhen is Mother's Day?
Persons: we've, It's, Mason, Farmgirl, they're Organizations: Business, Mother's, Apple
The outlook is starting to look bright for biotech stocks, according to some. With markets now expecting the first rate cut to be in September rather than June or July, as previously thought, biotech stocks could start to do well. Biotech encompasses many different areas, but Citi has identified one with a $2.9 billion market — which it says is set for even more growth. It gave CSL a price target of $305, or nearly 11% potential upside. It gave Intellia a price target of $31, or 49% potential upside.
Persons: Morgan Stanley, Garadacimab, Ionis, Citi Organizations: Biotech, Citi, Ionis Pharmaceuticals, Intellia Therapeutics, CSL, Intellia
Sandra TorresTorres has a rare disorder called Laron syndrome that is caused by a genetic mutation. “This is how powerful this mutation seems to be.”What is Laron syndrome? Laron syndrome is a recessive gene, so only those who receive a copy from each parent will be affected. The condition leads to extreme obesity, a trigger for diabetes, heart disease, cancer and other diseases. While technically overweight at 100 pounds (45.4 kilograms), she was in good health, with no signs of diabetes or heart disease.
Persons: Paola Castro Torres, ” Torres, Torres, , ” Nathaly Paola Castro Torres, Sandra Torres Torres, , Valter Longo, Longo, Laron, Jaime Guevara, Aguirre, Guevara, ” Longo, ” Guevara, Andrew Freeman, Freeman, ” Hope, it’s Organizations: CNN, gerontology, University of Southern, of Endocrinology, Laron, Jewish Health Locations: Los Angeles, Quito, Ecuador, University of Southern California, Israel, Yemen, East, United States, Croatia, Ireland, Denver
CNN —Even if your genetics put you at greater risk for early death, a healthy lifestyle could help you significantly combat it, according to a new study. Individuals with genetic risk could extend their lifespan by up to 5.5 years with a healthy lifestyle, the data showed. “Adherence to a healthy lifestyle could substantially attenuate the lifespan reduction for individuals with genetic susceptibility to a shorter lifespan,” Li said. But researchers were able to identify four factors that were associated with the biggest impact on risk of early death. Making lifestyle changesBuilding a healthier lifestyle may sound like a major undertaking, but manageable steps can help you get there.
Persons: Xue Li, Dr, Aladdin Shadyab, Shadyab, Li, ” Li, , Rosamund Dean, , you’ve Organizations: CNN, School of Public Health, Zhejian Univeristy, of Medicine, University of California, National Institute for Data Science, Health, Medicine, Zhejiang University, US Centers for Disease Control, CDC, of Locations: China, University of California San Diego, of Columbia, Guam, Puerto Rico
These are all clinically documented cases of sleep sex, or sexsomnia, part of a family of sleep disorders called parasomnias that include sleepwalking, sleep talking, sleep eating and sleep terrors. “There certainly can be legal consequences from the sexual behaviors, particularly with minors, and also with aggressive behaviors during sleep,” Schenck said. Also called OSA, obstructive sleep apnea is a serious sleep malady in which breathing stops for 10 seconds to two minutes many times per hour each night. “It’s the breath holding or apnea from the obstructive sleep apnea that triggers the arousal, typically in men, which then triggers the sexual behaviors in sleep,” Schenck said. “It’s so interesting, because a lot of people with stress become hyposexual, not interested in sex,” Schenck said.
Persons: rouses, Carlos Schenck, , Schenck, ” Schenck, Jennifer Mundt, moan, “ You’re, , Yuliya Kirayonak, , Northwestern’s Mundt, it’s, Mundt, ” Mundt, you’re Organizations: CNN, Hennepin County Medical, University of Minnesota, Northwestern University’s Feinberg School of Medicine, sexsomnia, , US Centers for Disease Control Locations: Hennepin, Norway, Chicago
The Food and Drug Administration on Friday approved Pfizer 's treatment for a rare genetic bleeding disorder, making it the company's first-ever gene therapy to win clearance in the U.S. The agency greenlit the drug, which will be marketed as Beqvez, for adults with moderate to severe hemophilia B who meet certain requirements. Without that protein, called factor IX, patients with hemophilia B bruise easily and bleed more frequently and for longer periods of time. The gene therapy will compete with Australia-based CSL Behring's Hemgenix, a similar treatment that won FDA approval for hemophilia B in 2022. The company is also developing a gene therapy for Duchenne muscular dystrophy, a genetic disorder that causes muscles to weaken gradually.
Persons: IX, hemophilia, Adam Cuker, Cuker Organizations: Drug Administration, Pfizer, U.S, Penn's, Spark Therapeutics, hemophilia Locations: U.S, Australia
Federal regulators on Friday said that they had not yet discovered live bird flu virus in the first batch of retail milk samples they tested, a reassuring indication that the milk on store shelves remains safe despite an outbreak of the virus among diary cows. In an online update, the Food and Drug Administration said an initial set of tests looking for live virus, not just genetic fragments, suggested that the pasteurization process was effectively neutralizing the pathogen. “These results reaffirm our assessment that the commercial milk supply is safe,” the F.D.A. wrote in the update, adding that the testing efforts were ongoing. Officials also tested infant and toddler formula, which incorporate powdered dairy, and did not find the virus, the agency wrote.
Organizations: Food and Drug Administration, Officials
In recent months the highly pathogenic H5N1 virus has been spreading through US cattle herds for the first time ever. The cow-to-cow transmission is the latest escalation in a global outbreak that began when the virus reemerged in Europe in 2020. Bill Powers with his flock of white turkeys, kept under shelter to prevent exposure to bird flu, in Townsend, Delaware. Nathan Howard/Getty ImagesDr. Jerome Adams, a former surgeon general and the director of health equity at Purdue University, is getting deja vu. AdvertisementOnly testing the sickSo far, the USDA has only been testing cattle herds when an animal appears sick.
Persons: , Jeremy Farrar, Nathan Frandino, Farrar, Bill Powers, Nathan Howard, Jerome Adams, they've, Adams, Donald Trump, hasn't, Terry Chea, they're, Zeynep Tufekci, Jean Carroll, Alexi J . Rosenfeld, President Trump, Trump, Biden Organizations: Service, Business, World Health Organization, Washington Post, Food and Drug Administration, New York Times, FDA, Johann, Reuters, US Centers for Disease Control, Purdue University, CDC, US Department of Agriculture, White, USDA Locations: Europe, South America, Fresno , California, Texas, Townsend , Delaware, COVID, Sonoma County , California
Federal regulators have discovered fragments of bird flu virus in roughly 20 percent of retail milk samples tested in a nationally representative study, the Food and Drug Administration said in an online update on Thursday. Samples from parts of the country that are known to have dairy herds infected with the virus were more likely to test positive, the agency said. Regulators said that there is no evidence that this milk poses a danger to consumers or that live virus is present in the milk on store shelves, an assessment public health experts have agreed with. But finding traces of the virus in such a high share of samples from around the country is the strongest signal yet that the bird flu outbreak in dairy cows is more extensive than the official tally of 33 infected herds across eight states. “It suggests that there is a whole lot of this virus out there,” said Richard Webby, a virologist and influenza expert at St. Jude Children’s Research Hospital.
Persons: , Richard Webby, Jude Children’s Organizations: Food and Drug Administration, Regulators, St, Jude Children’s Research
What if plants could talk to farmers and tell them when they're distressed? That would not only help the plants but also reduce the amount of agricultural waste that threatens the planet's health. Now companies like SatAgro, Climate FieldView, and a California-based startup called InnerPlant are working to reduce agricultural waste. From that signal, farmers know what to treat, meaning they don't waste money on chemicals, which are over-applied by up to 30%, Aronov said. In addition to Bison Ventures, InnerPlant is backed by John Deere, MS&AD Ventures, UpWest VC and Bee Partners.
Persons: Shely Aronov, Aronov, InnerPlant, Tom Biegala, John Deere, Lisa Rizzolo Organizations: Environmental Protection Agency, National Institute of Food, Agriculture, Bison Ventures, InnerPlant, AD Ventures, UpWest, Bee Partners, CNBC Locations: California, North America, South America
I think the possibility that the man could have fertility issues can be more than just a clinical concern. That isn’t the case, which is why it’s crucial to broaden our focus and address male infertility. Within this context, male infertility plays a significant role, contributing to around 40% of cases of infertility. Treating male infertilityTreating your male fertility issues can start right now. Don’t stay silentTackling male infertility requires care that extends beyond the confines of medical treatment.
Persons: Jamin, That’s, , you’re, what’s Organizations: Orlando Health, University of Central Florida’s College of Medicine, CNN, Consulting Locations: Alabama, United States
The outbreak of H5N1 avian influenza among U.S. dairy cows, first reported on March 25, has now spread to at least 33 herds in eight states. Federal authorities say the milk supply is safe, but this latest development raises troubling questions about how widespread the outbreak really is. Rick Bright, an expert on the H5N1 virus who served on President Biden’s coronavirus advisory board, told me this is the crucial moment. That’s when I told him what I’d heard from Sid Miller, the Texas commissioner for agriculture. The commissioner speculated that back then, as much as 40 percent of the herds in the Texas panhandle may have been infected.
Persons: Rick Bright, Biden’s, , it’s, I’d, Sid Miller, Bright, I’m, what’s Locations: Texas
With opulent graves but no written records, the empire and its people have remained largely in the shadows of history until recently. But a landmark April 2022 study involving ancient DNA taken from the graves of the Avar elite shed light on the empire’s far-flung origins. A tiny sample is drilled from a bone at the ancient DNA laboratory at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. In the case of men, researchers found two partners in 10 cases, three partners in four cases and four partners in one case. “Polygamy (having multiple marriage partners), serial monogamous marriages and extramarital relations are all possible explanations,” she said.
Persons: , Zsófia Rácz, Rácz, aren’t, Guido Alberto Gnecchi, Max Planck, Eötvös Loránd University Múzeum Lara Cassidy, , polygyny, Ruscone, Cassidy, Bryan Miller, wasn’t Organizations: CNN, of Archaeological Sciences, Eötvös Loránd, Múzeum, University’s, Archaeological Sciences, Max, Max Planck Institute, Eötvös Loránd University, Trinity College Dublin, Turks, Central, University of Michigan Locations: Central, Eastern Europe, Hungary, Rákóczifalva, Budapest, Leipzig, Germany, Europe, Mongolia, Caucasus, what’s, Constantinople, Byzantine, Eurasia
What it’s like to be a ‘glass child’
  + stars: | 2024-04-23 | by ( Taylor Nicioli | ) edition.cnn.com   time to read: +11 min
Meneses Maples refers to herself as an adult “glass child,” the sibling of a person with a mental or physical disability. How does a glass child disappear? It is important not to assume what the needs of a glass child are, said Missud, the New York psychotherapist. More than a decade after her TEDx presentation, Meneses Maples receives messages from parents of glass children seeking her advice. Meneses Maples said she hopes to inspire research on glass children by spreading the word through presentations and workshops.
Persons: Alicia Meneses Maples, David, Mario, Meneses Maples, didn’t, , ” Meneses Maples, Antonio TEDx, Debbie Missud, Emily Holl, Missud, ” Holl, , Holl, David couldn’t, Mario didn’t, , Shelley Cook, Laura Oliverio, Cook, Andrea, ” Cook, Cook didn’t, Shelley Cook “, Al Freedman, Freedman, Jack, Cara, Jack didn’t, ” Freedman, wasn’t, Alicia, Mario Meneses, Alicia Meneses Maples Meneses Maples, ‘ Alicia, ’ ” Meneses Maples, ’ ”, Organizations: CNN, Hulu’s, Suncoast, Disney, Cure SMA Locations: Chicago, Antonio, New York City, Glenwood Springs , Colorado, York
download the appSign up to get the inside scoop on today’s biggest stories in markets, tech, and business — delivered daily. Stephanie, 41, stepped up as our surrogate, while Meredith, another of my sisters, was our egg donor. AdvertisementStill, we did a total of six more rounds of IVF, costing more than $50,000. But we're a very close family — Stephanie, Meredith, and my youngest sister, Samantha, lived through every high and low of our IVF journey. Meredith and Stephanie presented us with the most special gift in the world.
Persons: , Jacyln, Stephanie, who'd, Jaclyn, Greg, We'd, Meredith, Turner, Mosaic Turner, Jaclyn Feiberg, endometriosis, Samantha, selflessness, didn't, David Berck, Barbara, hysterically Organizations: Service, Business, Health Locations: Westchester , New York
Ultragenyx Pharmaceutical has several growth opportunities ahead that could lead its share price to boom over the next year, according to RBC Capital Markets. Analyst Luca Issi initiated research coverage of the pharmaceutical company, which develops treatments for rare and ultra-rare diseases, with an outperform rating and $77 price target. Ultragenyx is forecasting between $500 million and $530 million in revenue for 2024, driven by rare bone disease drug Crysvita, long-chain fatty acid oxidation disorder drug Dojolvi, as well as therapies Mepsevii and Evkeeza. The analyst is also looking ahead to Ultragenyx's treatments for Angelman syndrome, Glycogen storage disease type 1, or GSD1a, plus Wilson's disease as potential opportunities to drive up the stock. Wilson's disease is a rare genetic disorder that prevents the body from eliminating copper, which then leads it to accumulate in the liver, brain and other organs.
Persons: Luca Issi, Issi, Issi's, Issa, GSD1a Organizations: Ultragenyx Pharmaceutical, RBC Capital Markets, U.S . Food, Drug Administration
CNN —More than 20 years after a mother found a human jawbone hidden in her son’s rock collection, genetic genealogy experts have unraveled the discovery and identified the partial remains of a US Marine Corps captain. In 2002, his mother found the collection, came across what looked to be human remains and contacted the sheriff’s office, authorities said in a statement. In January 2023, the sheriff’s office and the Yavapai County Medical Examiner referred the case to the Investigative Genetic Genealogy Center. The college partnered with the Yavapai County Sheriff’s Office to work on the case for free, the sheriff’s office said in a statement. “I think it shows how investigative genetic genealogy has stepped in and become the most really incredible investigative tool since the advent of DNA.”
Persons: Everett Leland Yager, John Doe, , ” Cairenn Binder, Binder, Bootcamp, Ethan Schwartz, Yager, ” Binder, , he’d, Yager’s, ” Gurney Organizations: CNN, US Marine Corps, Ramapo College of New, Office, Ramapo College, Genetic, GEDmatch Locations: Riverside County , California, Palmyra , Missouri, Yager, Yavapai County, Northern Arizona, Arizona, California, Yavapai, Ramapo, Salt Lake City , Utah, Salt Lake City
Does this mean people should start screening for cancer at younger ages? In the United States, lung cancer, colorectal cancer, pancreatic cancer and breast cancer are the four top causes of cancer deaths. For instance, in the United States, the US Preventive Services Task Force recommends that people begin colon cancer screenings at age 45. One in 3 people who are eligible for colon cancer screenings have never received any screening exams, according to the American Cancer Society. As little as one or two minutes of vigorous exercise a day can lower cancer risk, as can reducing ultraprocessed food.
Persons: Leana Wen, Wen, hasn’t, It’s Organizations: CNN, American Cancer Society, George Washington University, Oncology, US Preventive Services Task Force, Brigade Locations: United States
23andMe CEO Anne Wojcicki considers taking company private
  + stars: | 2024-04-18 | by ( Ashley Capoot | In | ) www.cnbc.com   time to read: +2 min
Anne Wojcicki, the CEO of 23andMe , is considering a proposal to take the genetic testing company private after its stock price tumbled more than 95% from its 2021 highs. She "wishes to maintain control" of the company and will "not be willing to support any alternative transaction," the filing said. 23andMe went public in 2021 via a merger with a special purpose acquisition company, which valued the company at around $3.5 billion. The company's board of directors formed a "Special Committee" in late March to help explore options that could juice the stock. "The Special Committee is committed to acting in the best interests of 23andMe and its shareholders."
Persons: Anne Wojcicki, Wojcicki, 23andMe, Wells Organizations: Securities and Exchange Commission, Nasdaq, Department Locations: Wells Fargo
He was a model to me of artistic labor and discipline, even if those early paintings were painfully amateurish. The painting followed me from Amherst to my first job in New York, and on to London and Delhi. IT WASN’T MY intention to start an essay about artistic beginnings with a story of artistic death. I’m especially moved by those first moments of validation by which an artist comes out to himself, as it were. It’s this, the inexorability of the correspondence between an artist and the world, that gives those first steps their magical quality.
Persons: Naipaul, Neil Shah, James Wood —, Zack, who’d, , Artemisia Gentileschi, Susanna, Elders ”, I’m, ” Gustave Flaubert, , ” Zack, it’s, Bruce Chatwin, Paul Gauguin, Salman Rushdie, Somerset Maugham, Kathryn Bigelow, Philip Glass, Arundhati Roy, Booker, Joseph Conrad, Conrad, Jacques, ” Conrad, brimming, , ’ ”, Clarice Lispector, Benjamin Moser, ” Lispector, Maugham, eludes, Jan van Kessel, Elder, — Pieter Bruegel, , Rebecca West —, “ Black Lamb, J.R, Hammond, Wells, Rebecca West ”, sloughed, Henrik Ibsen’s, Rosmersholm ”, Karan Mahajan, Salman Toor, what’s, ” Hemingway, Anoushka Shankar, Ravi Shankar, Harold Bloom, Ravi, Uday, René Daumal, Rasa ”, ” Anoushka, Norah Jones, Norah, I’ve, “ Raphael, Rachel Cusk, Italy ”, Perugino, Raphael, Cusk, J.M, Samuel Beckett, Gabriel García Márquez, Thomas Pynchon’s, James Joyce, Michelangelo, Leonardo da Vinci, Marcel Proust’s, Fyodor Dostoyevsky, Read, Emma Kehlbeck, Quinton Kamara Organizations: Amherst College, Elders, Fayerweather, , Google, Sunday Times, Somerset, Yugoslavia, The, , . Locations: Delhi, , Massachusetts, Italian, Topeka, Kan, Amherst, New York, London, Patagonia, New Delhi, Torrens, Cambridge, Polish, Ukrainian, Brazil, Flemish, Victorian England, “ H.G, Fairfield, United States, , East, Lahore, Europe, America, Texas, Side, Manhattan, India, Italy
Rates of colorectal cancer in people under 50 have been rising by 2% each year since 2011, according to the American Cancer Society. Iron deficiency anemiaIron deficiency anemia, which is where a person has low iron levels, can be a sign of colon cancer. Advertisement"When someone is found to have iron deficiency anemia, I think the important question is always going to be 'why is the person having iron deficiency anemia?' Unintentional weight lossUnintentional weight loss can be a symptom of any type of cancer, including colon cancer, Cleary said. AdvertisementAbdominal painAbdominal pain, aches, or cramps that don't go away could also be an indication that a person has colon cancer.
Persons: Dr, James Cleary, , it's, Cleary, that's Organizations: Service, American Cancer Society, Centers for Disease Control, CDC, Mayo Clinic, Dana, Farber Cancer Institute, Cancer Locations: Boston
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